METAPHASE FISH–15Q–DELETION-PRADER WILLI SYNDROME

Description

Fluorescence in situ hybridization (FISH) is a cytogenetic technique used to detect deletions or duplications of specific DNA sequences on chromosomes. In the context of Prader-Willi Syndrome (PWS), FISH is employed to identify deletions in the 15q11-q13 region, which is the most common genetic cause of PWS.