Description
In IVF, FISH analysis of follicular fluid can help detect X chromosome mosaicism, which is the presence of cells with different numbers of X chromosomes within the ovary. This technique involves examining cells from the follicular fluid, which surrounds the egg, during oocyte retrieval, using fluorescent in situ hybridization (FISH) to identify chromosomal abnormalities, including X chromosome variations. This method can be a valuable tool for assessing gonadal mosaicism and potentially predicting IVF outcomes.
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