FISH FOR T(14;18)/ IGH-BCL2

Description

FISH (Fluorescence In Situ Hybridization) for t(14;18)/IGH-BCL2 is a molecular diagnostic test used primarily to detect the translocation between chromosomes 14 and 18, specifically the fusion of the IGH (Immunoglobulin Heavy locus) and BCL2 genes. This translocation is a hallmark of follicular lymphoma and is also found in some other non-Hodgkin lymphomas. The test helps in diagnosing and monitoring these lymphomas by identifying the abnormal presence of the IGH-BCL2 fusion gene.