FISH FOR RARA BREAKAPART REARRANGEMENT

Description

FISH (Fluorescence In Situ Hybridization) with a RARA (Retinoic Acid Receptor Alpha) break-apart probe is a molecular cytogenetic technique used to detect rearrangements of the RARA gene, often associated with acute promyelocytic leukemia (APL). This method helps identify translocations, inversions, or other structural changes involving the RARA gene, which can be crucial for diagnosis and treatment monitoring in APL.