Description
FISH for IGH (14q32) rearrangement is a molecular cytogenetic technique used to detect specific chromosomal abnormalities involving the Immunoglobulin Heavy Chain (IGH) gene, located on chromosome 14q32. This test is particularly important in diagnosing and classifying B-cell lymphomas and multiple myeloma. It helps identify translocations (fusions of two different chromosomes) and other structural changes within the IGH locus, which can drive abnormal gene expression and contribute to the development of these cancers.



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