FISH FOR DELETION 22Q SYNDROME /CATCH 22

Description

Fluorescence in situ hybridization (FISH) is a diagnostic test used to detect the 22q11.2 deletion, which is the underlying cause of CATCH 22 syndrome (also known as 22q11.2 deletion syndrome, DiGeorge syndrome, or velocardiofacial syndrome). FISH uses fluorescently labeled DNA probes that bind to specific regions on the chromosome, allowing for the identification of deletions or duplications. In the case of 22q11.2 deletion syndrome, a probe targeting the region on chromosome 22q11.2 is used to detect the deletion.