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FISH FOR CLL 1 SET (CHR. 12 AND DEL 13Q OR DEL P53 AND DEL ATM)

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The FISH (Fluorescence In Situ Hybridization) test for Chronic Lymphocytic Leukemia (CLL) is designed to identify specific chromosomal abnormalities that have prognostic significance. The “1 set” likely refers to a panel of probes targeting specific chromosomal regions: deletion of 13q (13q14), trisomy 12, and deletions of TP53 (17p13) and ATM (11q22-23). These abnormalities are frequently found in CLL and are associated with different prognoses.

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Description

The FISH (Fluorescence In Situ Hybridization) test for Chronic Lymphocytic Leukemia (CLL) is designed to identify specific chromosomal abnormalities that have prognostic significance. The “1 set” likely refers to a panel of probes targeting specific chromosomal regions: deletion of 13q (13q14), trisomy 12, and deletions of TP53 (17p13) and ATM (11q22-23). These abnormalities are frequently found in CLL and are associated with different prognoses.

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