FISH FOR ANY ONE MICRODELETION SYNDROME WITH KARYOTYPING

Description

FISH (Fluorescence In Situ Hybridization) is a molecular cytogenetic technique used to identify microdeletion syndromes. It is particularly useful when karyotyping, which analyzes the overall chromosome structure, is inconclusive or unable to detect smaller deletions. While karyotyping can reveal large chromosomal abnormalities, FISH uses fluorescently labeled DNA probes to target specific regions on chromosomes, allowing for the detection of smaller deletions that may cause microdeletion syndromes.