FISH – DOWN’S SYNDROME

Description

FISH (Fluorescence in situ hybridization) is a diagnostic test that can be used to detect Down syndrome, which is caused by an extra copy of chromosome 21 (trisomy 21). FISH uses DNA probes that are labeled with fluorescent dyes to identify specific chromosome regions. In the case of Down syndrome, probes for chromosome 21 are used to determine if there are three copies instead of the usual two.