BETA THALASSEMIA 20 MUTATIONS (COUPLE)

Description

For a couple where both individuals carry a β-thalassemia trait (meaning they each have one mutated and one normal copy of the HBB gene), there’s a 25% chance with each pregnancy that their child will inherit two mutated genes, resulting in β-thalassemia major, a severe form of the disease. There is also a 50% chance the child will inherit one mutated gene and be a carrier like the parents, and a 25% chance the child will inherit two normal genes and not have the condition or be a carrier.