FISH FOR BCL6 BREAKAPART REARRANGEMENT

Description

FISH (Fluorescence In Situ Hybridization) for BCL6 gene rearrangement, specifically using a break-apart probe, is a molecular diagnostic test used to detect translocations involving the BCL6 gene at 3q27 in formalin-fixed, paraffin-embedded (FFPE) tissue specimens. This test is primarily used in the diagnosis and classification of B-cell lymphomas, aiding in identifying aggressive subsets of these cancers.