C MYC (ALL, NHL)

Description

In Non-Hodgkin Lymphoma (NHL), the c-MYC gene plays a significant role, particularly in B-cell lymphomas. Dysregulation of c-MYC, leading to overexpression, is a key event in lymphomagenesis, particularly in aggressive B-cell lymphomas. c-MYC is a transcription factor that regulates cell growth, proliferation, and apoptosis, and its dysregulation can lead to cancer.