BETA THALASSEMIA 6 MUTATIONS

Description

Beta thalassemia is a genetic blood disorder caused by mutations in the HBB gene, which codes for the beta globin chain of hemoglobin. These mutations can lead to reduced or absent beta globin production, resulting in decreased hemoglobin levels and anemia. Several common mutations account for a large proportion of beta thalassemia cases globally, including IVS-I-5 (G->C), IVS-I-1 (G->T), codon 8/9 (+G), codon 41/42 (-TCTT), and codon 15 (G->A).